We have had instances where our Zebra GK420 D printers would do this,
We found that using the Zebra ZP 450 driver corrected this even though its not for said device or model number.
Hate to say it but it prints the label upside down now, lol.
It doesn’t bother me but the people on the floor are complaining.
I tried going into the Printer Preferences and selecting 'Rotate 180 degrees but that did nothing.
I have not been successful flipping the SSRS report behind the labels, I think its because our current version off SSRS doesn’t support the expression to flip.
Other than that, possibly order labels that are wound the opposite direction? if the image coming out upside down is a huge issue, seems a bit trivial to me as the label can be applied right side up still after it prints.